The combined efficacy of neem (Azardirachta indica) seed oil and orange (Citrus sinensis) peel oil cream as a mosquito repellent

Essential oils obtained from certain plants have repellent potency against insects such as mosquitoes. Most repellents on the market synthetic formulation of N, N-diethyl-3-methylbenzamide (DEET) main active ingredient. This study is an attempt to contribute search for effective plant-extracted essential oil, Neem and Orange alternative DEET. The oil Citrus sinensis (sweet orange) peels was extracted by steam distillation that Azadirachta indica (Neem) seed Soxhlet extraction respectively. Creams were formulated at four concentrations 5%, 15%, 25% 30% v/w respectively Neem, peel combined Neem-Orange oils, after which laboratory reared mosquitoes used assess efficacy each concentrations. A DEET-based cream 13% concentration standard. Wild mosquito larvae brought adults female mating given a blood meal. Second generation arm in cage test (AIC). Orange-based recorded highest time, followed based least time even concentration. statistically significant difference between DEET peel, creams 0.030, 0 .499 0.195, suggests Peel Oil can be produce due their synergistic good smell.